Moe is the owner of the ratty bar, Moe's Tavern. He's the bartender and also has close relationships with some of the bar flies like Homer and Barney. Along with trying to commit suicide annually, Moe also has a liking for Marge, although he has referred to her sometimes as Midge.
The name Moe is short for Morris. As for his last name, it can be spelled Szyslak or Szyzlak. His most common customers include Lenny, Carl, Sam and Larry(as well as Homer and Barney mentioned above). Moe is seen as a cheap character who wants his customers to drink as much as possible to keep the tab going up. His love life usually seems grim due to his ugly appearance and his questionable attitude. Despite that, he's still had a few love affairs, and even during one episode he had plastic surgery which got him plenty of women during that short time.
Moe has also been the subject of most of Bart Simpson's prank calls. Every time, it has caused Moe to infuriate himself and respond back with angered comments and menacing threats, all of which makes Bart crack up with laughter. Lisa was also an accomplice in the older episodes. The one exception is the Hugh Jazz name which Bart suggested in The Flaming Moe episode, as Moe called out the name and an actual Hugh Jazz answered the phone, causing Bart's prank to fail.
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Moe: Call this an unfair generalization if you must, but old people are no good at everything.